Tweetie is the best everyday social feed interface I've ever seen. I'd love to see a future version support Facebook's newly-exposed stream API as an alternate "account," right along side Twitter accounts. A first version could map entirely to the existing Twitter metaphors: comments appear as linked @replies, photos and other shared items appear as links at the end of the post, etc. With your design skills, I'm certain a reasonable subset of Facebook feed functionality could be very usefully delivered without radically extending the core list GUI to support nested comments and inline photos and other such items which characterize the official Facebook feed. This should be more than sufficient to provide a fairly powerful and nice desktop interface to the Facebook feed, and all the non-Twitter-friends it contains for so many of us.