Skitch always takes a little while to respond after I haven't used it for a while. I acknowledge that it's not alone - all LSUIElement applications that live as system status items seem to be a little slow off the mark (including my own - Hyperspaces), however I wonder if it's just me?
Is anyone else seeing really slow responses when activating skitch? This happens whenever the machine has a couple of apps open - not under heavy load. I'm running on a 2.5Ghz MacBook Pro (Santa Rosa Series) with 2Gb RAM and a 7200 rpm drive.