Free Energy Function in EteRNA

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Hello. I would like to know a little more about the free energy function used to score structures in EteRNA. What is the formula used? Is it in a paper and if so which one? Thanks a lot!
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Digital

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Posted 8 years ago

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Jeehyung Lee, Alum

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Hi Digital,

We use a software called ViennaRNA to calculate free energies and the software is built on this paper.

http://bio.gsnu.ac.kr/research/miRNA/...
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Digital

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Hi Jeehyung: Thanks a lot for the prompt reply. While it is fun to play with EteRNA I want to try to understand why the changes I make in the structures produce the effects they do. Hopefuly the paper will answer some of these questions.
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Adrien Treuille, Alum

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Also, you can find out a lot by querying the forums for "energy."