Supercomputer 14

  • 1
  • Question
  • Updated 3 years ago
Hi everybody,
I read a lot of thing about this level, I've tried for along time, but I can't do it !
Is anybody can help me ?
Thanks
Photo of elasmo

elasmo

  • 1 Post
  • 0 Reply Likes

Posted 3 years ago

  • 1
Photo of whbob

whbob

  • 182 Posts
  • 56 Reply Likes
One of the comments says to place a C at the main RNA sequence # 66.  If you do that, look for a base in the TB-A oligo that would match this "C" base.  There are two.  #66-C will bind with TB-A # 106 or 100. Both are G's.  Continue to select bases from 67 and up to compliment the TB-A oligo.  It will take several bases to make a strong enough attraction to pull in TB-A.  When it does, see what happens to the MS2 hairpin. You need a series of bases that will break the MS2 hairpin. ( Hint: one will and one won't).
This is not a solution it is a start of a solution :)