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2416 RS485 Communication

We're having difficulty with 2416 device communicating via FTDI USB to serial converter. However the same device communicates with a serial card in the PC. We can see a signal when using the ET24xx LabView commands to talk to the device, but there's a timeout on the response as if the connection is not there. We've checked the baud rates and comm protocols on both ends, yet no communication. Any ideas?
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