Oxygen 49 and Cubase - No MIDI response with instrument track

In cubase I show midi activity in the transport when pressing Oxygen keys but the VSTs do not produce sound when the keyboard is played. In previously created projects the sound is great. I can use a Roland midi keyboard and all is well.

I can even play a standalone VST with the Oxygen and it works.

I can use the Oxygen to control the transport in cubase - just never any sound from the VST when using the Oxygen.

I'm stumped. I've reloaded the Oxygen driver twice now and the direct link works great.

Any Ideas?
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