Error 100s

This has been a nagging error for over 2 years with no end in sight. When will this error be fixed or is there a work-around? I uninstall, delete the mdb database and resinatall at least 4 times a week. What a crappy way to use a software....
The exact error message is
Mixmeister encountered a configuration error and cannot continue please make sure that the software is installed correctly. Error 100
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