How much memory should Thunderbird be using?

I have recently been getting low on memory warnings in Vista, which hasn't happened before. According to Windows Task Manager, Thunderbird is using over 50,000 K of memory. Is this what I should expect? Is there any way to reduce it? Does the fact that I have three email addresses active affect the memory use (although I have had 3 or 4 addresses active for some time and this problem just started)?
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