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Your Thunderbird profile cannot be loaded. It may be missing or inaccessible.

Had a major computer crash while we were out. Don't know what happened. Have used an undelete file to recover some of our e-mails but each time I try to open Thunderbird I get the following message - " Your Thunderbird profile cannot be loaded. It may be missing or inaccessible." Tried unistalling older version and installing latest version hoping it would require a new profile set up. Am currently running undelete program to try to recover our old profiles. My wife's profile is still visible but may be damaged because Thunderbird won't open on her profile either - same message. Anything else I can do? I really need to recover some of the old messages.
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